{"id":37404,"date":"2025-12-22T18:45:48","date_gmt":"2025-12-22T17:45:48","guid":{"rendered":"https:\/\/www.dexeuscampus.com\/blog\/sense-categoria\/el-dual-trigger-no-aporta-millors-resultats-que-lus-exclusiu-de-gnrh-a-en-preservacio-electiva\/"},"modified":"2025-12-29T16:53:51","modified_gmt":"2025-12-29T15:53:51","slug":"dual-trigger-resultats-gnrha-preservacio-electiva","status":"publish","type":"post","link":"https:\/\/www.dexeuscampus.com\/ca\/blog\/reproduccio-assistida\/dual-trigger-resultats-gnrha-preservacio-electiva\/","title":{"rendered":"El \u201cdual trigger\u201d no aporta millors resultats que l\u2019\u00fas exclusiu de GnRH -a en preservaci\u00f3 electiva"},"content":{"rendered":"\t\t
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Article:<\/p>\r\n

Dual trigger vs. gonadotropin-releasing hormone agonist trigger for elective fertility preservation: a randomized controlled trial<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Valeria Donno, Ana Raquel Neves, Sandra Garc\u00eda-Martinez, Ignacio Rodriguez, Nikolaos Polyzos.
Fertil Steril<\/strong>. 2025 Sep 16:S0015-0282(25)01913-2.
DOI: 10.1016\/j.fertnstert.2025.09.016<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Un equip de Dexeus Dona<\/strong>, liderat per la Dra. Valeria Donno<\/strong>, ha realitzat un estudi que compara dues estrat\u00e8gies diferents per induir la maduraci\u00f3 fol\u00b7licular abans de la punci\u00f3 fol\u00b7licular: el \u201cdual trigger\u201d (dues injeccions: hCG + agonista de GnRH) enfront de l\u2019\u00fas exclusiu de l\u2019agonista de GnRH. L\u2019estudi se centra en pacients amb bon pron\u00f2stic que decideixen dur a terme un tractament de preservaci\u00f3 de la fertilitat.
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L\u2019objectiu d\u2019aquest treball era determinar si hi ha difer\u00e8ncies en el nombre d\u2019o\u00f2cits madurs \u2014els realment rellevants per a la congelaci\u00f3 i per a futurs tractaments\u2014 quan s\u2019utilitza la doble injecci\u00f3 del \u201cdual trigger\u201d en comparaci\u00f3 amb una \u00fanica injecci\u00f3 amb agonista de GnRH.<\/p>

L\u2019assaig es va dur a terme entre l\u2019octubre del 2021 i l\u2019abril del 2023 i va incloure un total de 109 dones. Les pacients tenien \u226440 anys, un recompte de fol\u00b7licles antrals <20 i un nivell d\u2019hormona antim\u00fclleriana \u22643 ng\/mL. Els resultats van mostrar que no hi havia difer\u00e8ncies significatives en el nombre total d\u2019o\u00f2cits ni en el nombre d\u2019o\u00f2cits madurs entre tots dos grups. Tampoc no es van apreciar difer\u00e8ncies en els nivells hormonals del dia posterior al \u201ctrigger\u201d. No es van registrar casos de s\u00edndrome d\u2019hiperestimulaci\u00f3 ov\u00e0rica en cap dels grups. <\/p>

Els autors conclouen que el \u201cdual trigger\u201d no aporta avantatges respecte a l\u2019\u00fas exclusiu de l\u2019agonista de GnRH en termes d\u2019o\u00f2cits madurs. Per tant, l\u2019\u00fas de l\u2019agonista de GnRH s\u2019hauria de considerar suficient per induir la maduraci\u00f3 ovocit\u00e0ria abans de la punci\u00f3 fol\u00b7licular en pacients de bon pron\u00f2stic que se sotmeten a una estimulaci\u00f3 ov\u00e0rica per a la congelaci\u00f3 d\u2019o\u00f2cits. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Un equip de Dexeus Dona, liderat per la Dra. Valeria Donno, ha realitzat un estudi que compara dues estrat\u00e8gies diferents per induir la maduraci\u00f3 fol\u00b7licular abans de la punci\u00f3 fol\u00b7licular: el \u201cdual trigger\u201d (dues injeccions: hCG + agonista de GnRH) enfront de l\u2019\u00fas exclusiu de l\u2019agonista de GnRH.<\/p>\n","protected":false},"author":3,"featured_media":37398,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[206],"tags":[],"class_list":["post-37404","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reproduccio-assistida"],"yoast_head":"\nEl \u201cdual trigger\u201d no aporta millors resultats que l\u2019\u00fas exclusiu de GnRH -a en preservaci\u00f3 electiva - Dexeus Campus<\/title>\n<meta name=\"description\" content=\"Un equip de Dexeus Dona, liderat per la Dra. 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