{"id":39288,"date":"2026-11-12T16:26:54","date_gmt":"2026-11-12T15:26:54","guid":{"rendered":"https:\/\/www.dexeuscampus.com\/blog\/sense-categoria\/dexeus-avalua-una-nova-estrategia-destimulacio-ovarica-amb-nomes-dues-injeccions\/"},"modified":"2026-11-12T16:28:47","modified_gmt":"2026-11-12T15:28:47","slug":"dexeus-nova-estrategia-estimulacio-ovarica-dues-injeccions","status":"publish","type":"post","link":"https:\/\/www.dexeuscampus.com\/ca\/blog\/reproduccio-assistida\/dexeus-nova-estrategia-estimulacio-ovarica-dues-injeccions\/","title":{"rendered":"Dexeus avalua una nova estrat\u00e8gia d\u2019estimulaci\u00f3 ov\u00e0rica amb nom\u00e9s dues injeccions"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"39288\" class=\"elementor elementor-39288 elementor-39277\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9168702 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9168702\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-70fec2b\" data-id=\"70fec2b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ef5400d elementor-widget elementor-widget-html\" data-id=\"ef5400d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p style=\"margin: 0px 0px 0px 0px; text-align: left; font-size: 17px; font-weight: 600; font-style: italic; color: #537b8d;\">Article:<\/p>\n<p style=\"margin: 5px 15px 0px 0px; text-align: left; font-size: 19px; font-weight: 400; font-style: italic; line-height: 24px; color: #4f91cd\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42786378\/\" target=\"_blank\" rel=\"noopener\" style=\"font-size: 19px; font-weight: 400; color: #4f91cd; text-decoration: underline;\" title=\"The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy\">The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-e336696 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e336696\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-7dc5693\" data-id=\"7dc5693\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e459e0a elementor-widget elementor-widget-html\" data-id=\"e459e0a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p style=\"margin: 0px 0px; text-align: left; font-size: 16px; font-weight: 400; font-style: italic;\">Valeria Donno, Noemie Sachs-Guedj, Marta Devesa, Sandra Garc\u00eda-Martinez, Ignacio Rodriguez, Nikolaos P Polyzos.<br\/><strong>Hum Reprod<\/strong>. 2026 Sep 25:deag142.<br\/>DOI: <a id=\"enlace_doi\" href=\"https:\/\/doi.org\/10.1093\/humrep\/deag142\" target=\"_blank\" rel=\"noopener\" style=\"font-size: 16px; color: #4f91cd; text-decoration: underline;\" title=\"10.1093\/humrep\/deag142\">10.1093\/humrep\/deag142<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-0abe33f\" data-id=\"0abe33f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b772d0b elementor-widget elementor-widget-image\" data-id=\"b772d0b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42786378\/\" target=\"_blank\" title=\"pubmed\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"250\" height=\"90\" src=\"https:\/\/www.dexeuscampus.com\/wp-content\/uploads\/2024\/06\/logo-human-reproduction.png\" class=\"attachment-full size-full wp-image-31808\" alt=\"Human Reproduction\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3f3252d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3f3252d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6c1b6e5\" data-id=\"6c1b6e5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9bafe9e elementor-widget elementor-widget-text-editor\" data-id=\"9bafe9e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Reduir el nombre d\u2019injeccions hormonals durant l\u2019estimulaci\u00f3 ov\u00e0rica sense comprometre els resultats \u00e9s un dels reptes per millorar l\u2019experi\u00e8ncia de les pacients en reproducci\u00f3 assistida. Un equip d\u2019investigadors de Dexeus Dona, liderat per la <strong>Dra. Valeria Donno<\/strong>, responsable d\u2019R+D del Servei de Reproducci\u00f3, ha avaluat un nou protocol d\u2019estimulaci\u00f3 ov\u00e0rica basat en dues administracions seq\u00fcencials de corifol\u00b7litropina alfa (CFA), una hormona d\u2019acci\u00f3 prolongada, com a alternativa al protocol convencional que combina CFA amb dosis di\u00e0ries de FSH recombinant.<\/p><p>L\u2019estudi, un assaig cl\u00ednic aleatoritzat de fase III, va incloure 194 dones menors de 40 anys que havien decidit preservar la seva fertilitat. La mostra es va dividir en dos grups. Tots dos grups van rebre un protocol d\u2019estimulaci\u00f3 amb progest\u00e0gens (PPOS) per evitar l\u2019ovulaci\u00f3 prematura. L\u2019objectiu principal era comparar el nombre d\u2019ov\u00f2cits madurs (MII) obtinguts. Els resultats van mostrar una mitjana d\u2019aproximadament 6 ov\u00f2cits en el grup d\u2019estudi, enfront de 7 en el grup de control, sense difer\u00e8ncies estad\u00edsticament significatives. Tanmateix, no es va assolir el criteri estad\u00edstic predefinit per demostrar la no-inferioritat del nou protocol. Tampoc no es van observar difer\u00e8ncies significatives en la durada de l\u2019estimulaci\u00f3 ni en el nombre de fol\u00b7licles de mida m\u00e9s gran, tot i que les concentracions de FSH van ser superiors en el grup experimental.<\/p><p>El principal inter\u00e8s cient\u00edfic de l\u2019estudi rau en la possibilitat de simplificar els protocols d\u2019estimulaci\u00f3 ov\u00e0rica controlada, reduint la c\u00e0rrega d\u2019injeccions sense que s\u2019hagin observat difer\u00e8ncies estad\u00edsticament significatives en el nombre d\u2019ov\u00f2cits madurs recuperats. No obstant aix\u00f2, els resultats requereixen confirmaci\u00f3 mitjan\u00e7ant nous estudis abans de recomanar-ne l\u2019aplicaci\u00f3 generalitzada. Aquesta l\u00ednia de recerca obre noves possibilitats per desenvolupar estrat\u00e8gies d\u2019estimulaci\u00f3 m\u00e9s senzilles i adaptades a les necessitats de les pacients.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Reduir el nombre d\u2019injeccions hormonals durant l\u2019estimulaci\u00f3 ov\u00e0rica sense comprometre els resultats \u00e9s un dels reptes per millorar l\u2019experi\u00e8ncia de les pacients en reproducci\u00f3 assistida.<\/p>\n","protected":false},"author":3,"featured_media":39279,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[206],"tags":[],"class_list":["post-39288","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reproduccio-assistida"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - 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