Researchers at the Institute for Bioengineering of Catalonia (IBEC) in collaboration with embryologists from the Reproductive Medicine Department at Dexeus Mujer–Hospital Universitari Dexeus have captured unparalleled images of a human embryo implanting. This is the first time that the process has been recorded in real time and in 3D.
To carry out the study, the IBEC research team developed a platform that allows embryos to implant outside the uterus under controlled conditions. This enables real-time fluorescence imaging and analysis of the embryo’s mechanical interactions with its environment. The platform is based on a gel composed of an artificial matrix formed by collagen, which is abundant in uterine tissue, and various proteins necessary for embryo development.
“Our work has involved providing technical advice and carrying out a rigorous selection of the human embryos donated for research, with the aim of ensuring they met the ideal conditions for the execution of the project,” explains Miquel Solé, director of the Laboratory of Criopreservation of Dexeus Mujer.
The study, published in the journal Science Advances, may help to better understand the mechanisms underlying the implantation process, improving fertility rates and optimising assisted reproduction processes.
Further information:
https://ibecbarcelona.eu/graban-por-primera-vez-el-proceso-de-implantacion-de-un-embrion-humano/