Is gestational diabetes more common in ART patients?

Diabetes gestacional: ¿más frecuente en pacientes de reproducción asistida?

Is gestational diabetes more common in ART patients?

The prognosis of gestational diabetes is similar in spontaneous and ART-conceived pregnancies

A team from the Obstetrics Department at Dexeus Mujer, led by Dr Gemma Sesmilo, conducted a retrospective analysis of prospectively collected data from singleton pregnancies monitored at the Hospital Universitari Dexeus between 2008 and 2019. Their aim was to study whether women who use assisted reproductive technology (ART) have a higher incidence of gestational diabetes (GDM) compared to those who become pregnant spontaneously, whether the ART technique used had an influence, and whether the obstetric outcomes of GDM were worse in women who underwent ART cycles. Women under 18 years of age or with pregestational diabetes, as well as multiple pregnancies, were excluded from the study.

A total of 29,529 patients were included. Pregnancy was achieved by ART in 2596 cases (8.8%): 32.8% in vitro fertilisation (IVF/ICSI), 37.7% frozen embryo transfer (FET), 17.2% oocyte donor recipients (ODR) and 12.2% IUI. The GDM rate was 8.9% (12.7% in ART pregnancies vs. 8.5% in non-ART pregnancies). GDM was 11.2% in IVF/ICSI pregnancies, 17.7% in ODR pregnancies, 13% in FET pregnancies and 9.1% in IUI pregnancies. A multivariate analysis adjusted for age, parity and BMI, did not associate GDM with ART nor with a specific ART technique.

Pregnancy outcomes in GDM patients were similar in both groups, except for caesarean section rates. The authors concluded that, despite a higher prevalence of GDM in ART-conceived pregnancies, there was no increased risk of GDM when adjusted for age, parity, and BMI. The prognosis of GDM in ART-conceived and spontaneous pregnancies was similar, except for caesarean section rates.

Reference study:
Gestational diabetes prevalence and outcomes in women undergoing assisted reproductive techniques (ART)
G. Sesmilo, P. Prats, M. Álvarez, I. Romero, M. Guerrero, I. Rodríguez, A. Rodríguez-Melcón, S. Garcia, B. Serra
Endocrinol Diabetes Nutr 2022 Dec;69(10):837-843. doi:10.1016/j.endien.2022.11.016.

How can we help you?

We inform you that the personal data that you provide by filling in this form will be treated by Dexeus Mujer Foundation as responsible for this website. The purpose of collecting and processing this data is to contact you regarding your request and in the event that you expressly authorize us to send you information on activities, promotions and / or services and our periodic newsletter. The legitimation is carried out through the consent of the interested party. You can exercise your rights of access, rectification, limitation and delete the data before the data protection officer at as well as the right to file a claim with a control authority. You can consult the additional and detailed information on Data Protection in our privacy policy.

¿Cómo podemos ayudarte?

Te informamos que los datos de carácter personal que proporciones rellenando el presente formulario serán tratados por Fundación Dexeus Mujer como responsable de esta web. La finalidad de la recogida y tratamiento de estos datos es contactar contigo en referencia a tu solicitud y en caso de que expresamente nos autorices enviarte información sobre actividades, promociones y/o servicios y nuestro boletín informativo periódico. La legitimación se realiza a través del consentimiento del interesado. Podrás ejercer tus derechos de acceso, rectificación, limitación y suprimir los datos ante el delegado de protección de datos en así como el derecho a presentar una reclamación ante una autoridad de control. Puedes consultar la información adicional y detallada sobre Protección de Datos en nuestra política de privacidad.